Pharmaceutical Facility Cleaning

We Clean to the Most Important Standards…Yours!

Source One specialized cleaning for pharmaceutical facilities.


You have a lot of important things on your plate. Most important is the development and manufacture of pure, safe and effective pharmaceutical products. You can’t risk particulate and bioburden contamination compromising your operations. 

Cleaning and sanitation steps hold the key to achieving great results. That means cleaning done by a company that is ISO- and GMP-certified. 

That’s what you get from SourceOne.

Life Science Facility Cleaning

When it comes to pharmaceutical and biotech cleaning, we take quality control very seriously. Each of our cleaning technicians undergoes extensive training in order to join our team and is always briefed on facility protocols and procedures before each job.

Commercial Janitorial Cleaning

We provide the most reliable janitorial services in the Northern California area to help you ensure that your work area is immaculate. Learn a little bit more about the commercial cleaning services that we offer and make sure that you contact us today to get started!

Industries Served

SourceONE focuses on clients where the quality of cleaning, safety, maintenance, and appearance is critical to the basic function of the establishment. We serve a wide variety of market sectors, including the following, with our vast expertise and superior quality.

We Don’t Have to Tell You, Cleaning is a Big Deal.

Cleaning and sanitation of pharmaceutical equipment and facilities account for almost one-third of all production activities. And with the FDA looking over your shoulder, you’re going to need fully documented procedures (SOP), and documented proof that the procedures have been followed meticulously.

That’s Why We Provide Rigorous Hands-on and Classroom Training for our Pharmaceutical Facility Cleaning Specialists.

At the end of the day, no matter how thorough and detailed your SOP is, it’s up to the people doing the work to ensure that it’s done to your standards, to FDA regulatory standards, with accurate, legible work logs that will stand up to scrutiny.

We place special emphasis on having a certified team that undergoes comprehensive training in clean rooms and controlled environments. Our employees have classroom experience and hands-on instruction before they’re ever allowed to go into a pharmaceutical company. They’re also going to be trained to your specific SOP. You wouldn’t want it any other way, and neither would we.

“We have specialized and highly trained cleaning crews for clean rooms, controlled environments, and laboratories. Rigorous training with regards to our clients’ SOPs.”  

John Nigro

You Can Always Tell That You’re Dealing With Pros When You Talk to SourceOne.

We know the questions to ask. We know where the problem areas are. We’ve been at this a while now and when needed, we solve problems. We’re resourceful and innovative. When Covid-19 hit, we developed intensive protocols so that facilities could remain open and do their essential work.

More about our Covid-19 solution

At the beginning of the COVID-19 outbreak in March 2020, SourceOne quickly designed a plan for our client to keep their employees safe and their facility open.

We proposed our Healthy Covid-Cleaning ProtocolsTM   program which includes a dedicated SourceOne technician to disinfect high-traffic areas and critical laboratories.

Together, we worked with our client to identify a list of high-touch surfaces and potential high-risk areas. SourceOne performed the day/night disinfection 6 days a week, in 6 different buildings. This included electrostatic spraying in high-risk areas such as conference rooms and bathrooms at night.

The result was a substantial decrease in Covid-19 cases.

a bottle being filled in a nutraceutical plant

Put Our Depth of Cleaning Knowledge, Experience and Expertise to Work at Your Facilities.

Whether you have a small research operation or a large production facility, you can count on SourceOne to deliver ISO and GMP/GLP certified cleaning. Our attention-to-detail and thorough documentation truly set us apart in pharmaceutical facility cleaning. 

We can tailor a cleaning schedule to your SOP. We can be your daily go-to or supplement your own team as much as you require. 

Discover the SourceOne difference.

Pharma Facility Cleaning Consulting

We offer newer facilities and start-ups resources and comprehensive consulting on required cleaning processes and procedures to ensure their compliance and for maintaining proper containment, sanitation, and waste disposal.

Ongoing Maintenance Programs

We develop customized maintenance programs tailored to your specific needs, ensuring consistent cleanliness and compliance throughout your facility.

Get SourceOne on Your FM Team

Let’s Take a Deeper Dive on Cleanrooms.

Cleanroom Maintenance

SourceOne provides secure contamination control from ISO 4-ISO 9, using ISO-compliant and GMP quality programs and environmentally friendly and sustainable solutions.

Microbial Control and Diversity

Cleanrooms are traditionally designed to minimize microbial contamination. However, recent studies have revealed a diverse range of microbes in cleanrooms, challenging the assumption of a completely sterile environment.

While cleaning efforts reduce the abundance of microbes, they do not significantly impact the diversity. Archaea, including survival specialists like bacterial spore formers and halophiles, have been found alive in cleanrooms.

Temperature, Humidity, and Atmospheric Pressure

Cleanrooms must meticulously control temperature, humidity, and atmospheric pressure levels. These factors are critical for maintaining consistency, reliability in test results, and minimize particulate contamination.

Antibiotic Resistance and Cleaning Practices

Stringent cleaning practices correlate with the emergence of antibiotic-resistant microbes. This poses challenges for containment and potential economic losses.

A Closer Look at GMP

The GMP rules are very explicit regarding the requirement to clean and sanitize equipment and the manufacturing facility. Your company’s standard procedures and cleaning records alone are evidence of proper cleaning.

1. Cleaning and Sanitation Procedures

GMP requires the cleaning procedures to be fully documented in written procedures. These procedures are initially validated (shown to be effective) specifically for an item of equipment or an area.

Once validated, the procedures are then published as the SOP and implemented with high levels of attention to detail.

2. Cleaning Validation

All cleaning procedures should be validated (shown to be effective) under specific conditions of use. These conditions of use are specified in the SOP.

Employees cannot deviate from the SOP or alter the conditions of use without risking invalidating the cleaning methods. For example, it would seem logical that adding using a stronger sanitizer than the procedure requires would make cleaning faster or better. This is not always the case as you may alter the properties of the solution (e.g. lowering the pH) thus rendering it less effective.

The relevant GMP rules are to only clean under validated conditions and strictly follow procedures. 

3. Cleaning and Sanitation Conditions

The written procedures describe the required conditions under which cleaning is optimal.

These conditions must be followed precisely or you risk unacceptable results. For example, too strong of a solution used in sanitizing could damage the surfaces of counters, tabletops, equipment and accessories. The pH balance has to be accurate or you could end encouraging bacteria growth instead of eliminating it.  Also, the type and quality of the water used can impact results. 


Your SourceOne team understands all of the variables and dials it all in for best results:

Title: Key Components for Optimal Cleaning Conditions

  • Strength of the cleaning or sanitizing agent (e.g., 2.0% v/v)
  • The type of water or solvent to be used
  • The pH of the cleaning agent
  • The temperature of the water to be used
  • How much to dismantle equipment before cleaning commences
  • The contact or residence time for the sanitizing agent on the surface
  • What agents to use to clean off the sanitizing agent
  • What standard of water to use in the final rinse (GMP, for example, requires purified water for injection as the final rinse)
4. Cleaning and Sanitation Records

One essential GMP rule is the keeping of detailed cleaning records. Cleaning records prove that cleaning took place and evidence of the cleaning outcomes.

For example, the surfaces are visually clean or the results of rinse water tests.

The records must also identify who did the cleaning and when and must be signed.

For automatic cleaning procedures such as clean in place (CIP), the cycle conditions are usually automatically monitored and the conditions recorded.

Cycle conditions may include the temperature, flow rate, time, concentration of solvent, and solvent agitation time. Often, CIP systems have alarms when something goes wrong.

The completed and signed records should be attached to the records since they provide the only objective evidence that cleaning has occurred.

What Must be Cleaned?
  • The facility must be regularly cleaned. Particular emphasis is placed on areas or rooms where product is processed.
  • Particular emphasis is placed on effectively cleaning all equipment in contact with the product, and it must be cleaned according to validated and detailed procedures.
  • All equipment in processing areas not in contact with the product needs regular cleaning to prevent dust and dirt buildup.
  • The inside of the factory should be regularly cleaned, but particular attention should be paid to the processing and storage rooms. The floors, surfaces, benches, walls, and ceilings should undergo cleaning at defined intervals.
  • Cleaning and sanitation also apply to any equipment in contact with the product during manufacture, such as production and packaging equipment, transfer lines and tanks, and storage containers and drums.
A person's hands using a spray bottle to clean a surface, with a fine mist in the air and a microfiber cloth, demonstrating thorough disinfecting procedures.

We Take Documentation Very Seriously…a Case Study.

Good Documentation Practices (GDP) are the measures that collectively and individually ensure documentation, whether paper or electronic, is secure, attributable, legible, traceable, permanent, contemporaneously recorded, original, and accurate. 

Compliant documentation builds confidence in the quality assurance system and practice. GDP ensures there is traceability in what is being documented. This process is useful for reviews and investigations. A reduction in assumptions/second guessing around procedures that are carried out by the SourceONE team is also a result of this process. Effective documentation practices provide consistent quality, performance of staff, and specifies clear instructions on what has been accomplished with the controlled environment.

Poor Documentation Practices Include: 

  • Missing signatures and dates at the time an activity was performed
  • Non-uniform date and signature
  • Activities performed on one day and signed for on another day.
  • Illegible handwriting
  • Too many corrections & missing reasoning within corrections
  • Spaces being left blank and using white out or other masking devices

One of SourceOne’s Life Sciences clients come to us because of continual issues and lapses in GDP (Good Documentation Practice) including missing entries, improper entries, and corrections. 

SourceONE addressed this by providing retraining on how to properly review logbooks. The client’s Quality Assurance team created a GDP tracker where all errors found on client-controlled logbooks and corrections made in logbooks are recorded to increase visibility into site documentation. Together, we created a QR code that supervisors can use to track a procedure to review client logbooks and perform any corrections. The QR code acts as a supplement to training.

Following the implementation, the clients noted a significant reduction in GDP errors.

At SourceOne, our focus is always on ensuring that your established processes are failsafe to keep your site production capable.

Pharmaceutical FAQs


SourceOne focuses on the Life Sciences industry with specific focus on biotechnology, pharmaceutical, and medical device laboratories (R&D) and manufacturing facilities.


The nature of Life Sciences work creates serious challenges for facility managers due to the need for high standards of cleaning required to combat contamination from bacteria, mold and virus. 


We begin with an assessment to determine the standards and protocols required to achieve the appropriate level of cleanliness for your specific facility. This includes ISO cleanroom standards and BSL (Biological Safety Levels).


GMP stands for Good Manufacturing Practices which is a system that consists of processes, procedures and documentation that ensures products are consistently produced and controlled according to set quality standards. Implementing GMP cleaning protocols can help cut down on losses and waste. Overall, it protects both company and consumer from negative safety events.


Your SourceOne team undergoes comprehensive training and thorough classroom and hands-on instruction in cleanroom and controlled environment practices, tailored to the unique needs of life science facilities including biotechnology, pharmaceuticals, and medical devices.


Biopharma products demand a strict stand against contaminants of all types. Additionally, in the ever-evolving realm of biopharma, where new innovations emerge frequently, GMP cleaning remains the consistent foundation ensuring product and worker safety and efficacy.


If you are launching a new Life Sciences venture and need to develop a cleaning and sanitation SOP, we can provide consulting services that include an audit of your facility and operations. Together we will build a detailed cleaning plan that conforms with all necessary ISO/GMP procedures and protocols, along with Good Documentation Practice log books.

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Contact SourceOne

SourceONE Building Maintenance, Inc. Corporate Headquarters

2974 Scott Blvd.
Santa Clara, CA 95054

Phone: 408-437-3046

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Life Sciences Facilities

Whether you run a biotech research lab, a pharmaceutical manufacturing plant, or a medical device testing lab, you face specific challenges, standards, regulations and protocols for maintaining a safe, sterile environment for your scientists and technicians.

Pharmaceutical Facility Cleaning

The pursuit of excellence in healthcare begins with maintaining clean and hygienic spaces where drugs are manufactured, tested, and packaged.

Biotech Facility Cleaning

This is one area of business operation that demands quality control, which is exactly what SourceONE’s laboratory cleaning services provide.

Medical Device Facility Cleaning

With our meticulous approach and advanced cleaning techniques, we offer peace of mind, knowing that every medical device is thoroughly sterilized and free from contaminants.

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